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Daniel Genis was on Pat Dixon's radio show in New York recently, which reminded me how much fun it was having Pat on our show -- but Daniel is easier to get hold of, and he can't resist media exposure. Plus we have sort of a Mission Impossible relationship with Daniel.
Your mission, should you choose to accept it, is to score some Fentanyl and tell us what the hell is going on....we hoped he knew that we were half kidding. We never want to endanger Daniel just when he is about to get even more famous, but he called back to say "Mission Accomplished"
which means he got the dope of Fentanyl, or he invaded some sovereign nation on some bogus pretext...or both.
Here is the basic fact sheet on Fentanyl so you know what we are talkin' 'bout, Willis.
Fentanyl is the generic form of the brand-name drug Duragesic, a prescription opioid (narcotic) drug used to treat chronic, "around-the-clock" pain.
It should be used only by people who are "opioid-tolerant," or who are already taking opioid pain medications, such as morphine and oxycodone, regularly.
Fentanyl is in a class of drugs called opioid analgesics, which work by binding to nervous system proteins called opioid receptors, thereby blocking the transmission of pain signals to the brain.
Duragesic is a transdermal (through the skin) patch.
Fentanyl is also sold as a lozenge under the brand name Actiq, a tablet that goes under the tongue (Abstral), a film that's applied to the inner lining of the cheek or lip (Onsolis), a tablet that goes between the gum and cheek (Fentora) a nasal spray (Lazanda), a sublingual tablet (Abstral), and a sublingual spray (Subsys).
The Food and Drug Administration (FDA) first approved fentanyl, which is produced by Johnson & Johnson, in 1968.
Over the years, Johnson & Johnson has issued several recalls of its Duragesic pain-relief skin patches.
In 2004 and 2008, the company recalled some of its patches because of damage that could have caused the medication to leak potentially fatal fentanyl gel.
In 2012, Johnson & Johnson recalled more than 53,000 Duragesic patches after fentanyl crystals were found in a patch (the drug is supposed to be completely dissolved).
Fentanyl Abuse
Fentanyl use can lead to addiction, abuse, and misuse, even at the recommended doses — this risk is higher for people with a personal or family history of substance abuse or mental illness.
Fentanyl is almost 100 times more potent than morphine, but the drug is designed to deliver small amounts of fentanyl each hour over an extended period of time.
When ingested, however, the Duragesic patch can deliver its entire dose all at once, increasing the risk of an overdose.
In 2008, a study in the Journal of Forensic Sciences reviewed seven case reports of oral abuse of Duragesic and found that fentanyl overdose caused or contributed to the deaths of the persons in each case.